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What is the best way to backup Zimbra Open source running on a Hyper-V VM?

[quote user="crandall348"]What is the best way to backup Zimbra Open source running on a Hyper-V VM?[/QUOTE]
Any of the methods in the wiki or forums will do the job. I'd suggest you try them and see which ones fit your requirements (including the disaster recovery scenario). When you've tested a backup and restore then document the complete procedure to make sure every admin knows how to do it.
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If I stop Zimbra Services, then manually copy the /opt/zimbra folder using WinSCP, will this cause any issues?

no, unless you can afford downtime each time
I recommend rsync if you want to do that so you can restore whole folder later via rsync too, or try searching on wiki for livesync to setup cold stanby server

[quote user="umarzuki"]no, unless you can afford downtime each time[/QUOTE]For the Open Source version of Zimbra you have to stop all the services when taking a backup even with rsync otherwise the backup cannot be guaranteed to be in a consistent state and may be impossible to restore.

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I am using the Open Source. So, since there will be downtime anyway, I could use WinSCP to copy, correct.

Have you tried Veeam?
Veeam Backup Free Edition for VMware and Hyper-V VMs (VeeamZIP)
I never tried it myself but it's free version's features seems interesting

Has anybody used Veeam Backup with Zimbra Open Source?

[quote user="crandall348"]Has anybody used Veeam Backup with Zimbra Open Source?[/QUOTE]

I used VEEAM backup (free version) to backup VM on ESXi 5.1

Normally, before configure any thing on Zimbra mail server, I take a snap shot. Full backup is carried out at weekend.